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Ligand-binding and heterodimerization activities of a conserved region in the ligand-binding domain of the thyroid hormone receptor.

The ligand-binding domain of the thyroid hormone (3,5,3'-triiodothyronine) receptor (TR) contains poorly characterized subdomains involved with ligand binding, transactivation, and protein-protein interactions. The region between residues 288-331 of rat TR alpha-1 was analyzed by modeling and site-d...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Spanjaard, R A, Darling, D S, Chin, W W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52554/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924318/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8587
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