Architectural Role of Mitochondrial Transcription Factor A in Maintenance of Human Mitochondrial DNA

Mitochondrial transcription factor A (TFAM), a transcription factor for mitochondrial DNA (mtDNA) that also possesses the property of nonspecific DNA binding, is essential for maintenance of mtDNA. To clarify the role of TFAM, we repressed the expression of endogenous TFAM in HeLa cells by RNA inter...

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Detalhes bibliográficos
Main Authors: Kanki, Tomotake, Ohgaki, Kippei, Gaspari, Martina, Gustafsson, Claes M., Fukuoh, Atsushi, Sasaki, Narie, Hamasaki, Naotaka, Kang, Dongchon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525493/
https://ncbi.nlm.nih.gov/pubmed/15509786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.22.9823-9834.2004
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