Regulation of Cell Cycle-Specific Gene Expression through Cyclin-Dependent Kinase-Mediated Phosphorylation of the Forkhead Transcription Factor Fkh2p

The forkhead transcription factor Fkh2p acts in a DNA-bound complex with Mcm1p and the coactivator Ndd1p to regulate cell cycle-dependent expression of the CLB2 gene cluster in Saccharomyces cerevisiae. Here, we demonstrate that Fkh2p is a target of cyclin-dependent protein kinases and that phosphor...

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Bibliographic Details
Main Authors: Pic-Taylor, Aline, Darieva, Zoulfia, Morgan, Brian A., Sharrocks, Andrew D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC525469/
https://ncbi.nlm.nih.gov/pubmed/15509804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.22.10036-10046.2004
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