Effects of Amoxicillin Subinhibitory Concentrations on the Cross-Protection Developed by Pneumococcal Antibodies in Mouse Sepsis Caused by an Amoxicillin-Resistant Serotype 6B Streptococcus pneumoniae Strain

A model of mouse sepsis caused by a serotype 6B Streptococcus pneumoniae strain (amoxicillin MIC of 8 μg/ml) was developed to investigate the therapeutic effect of an amoxicillin dose (3.12 mg/kg of body weight three times daily for 48 h) producing, over the whole treatment period, subinhibitory con...

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Bibliographic Details
Main Authors: Tarragó, D., Aguilar, L., Giménez, M. J., Fenoll, A., Casal, J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC525454/
https://ncbi.nlm.nih.gov/pubmed/15504833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4144-4147.2004
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