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Hypermutation and the Preexistence of Antibiotic-Resistant Pseudomonas aeruginosa Mutants: Implications for Susceptibility Testing and Treatment of Chronic Infections

Whether or not resistant mutants will be present before the start of antibiotic treatment of an initially susceptible population of bacteria depends on the size of the infecting population, the rate of mutation to resistance, and the amount of time that the population has been maintained. In the pre...

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Detalhes bibliográficos
Main Authors: Oliver, Antonio, Levin, Bruce R., Juan, Carlos, Baquero, Fernando, Blázquez, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525420/
https://ncbi.nlm.nih.gov/pubmed/15504845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4226-4233.2004
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