LB11058, a New Cephalosporin with High Penicillin-Binding Protein 2a Affinity and Activity in Experimental Endocarditis Due to Homogeneously Methicillin-Resistant Staphylococcus aureus

LB11058 is a new synthetic cephalosporin with good affinity for staphylococcal penicillin-binding protein 2a (PBP2a). LB11058 was tested in vitro and in rats with experimental aortic endocarditis against three methicillin-resistant Staphylococcus aureus (MRSA) strains, one penicillinase-negative str...

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Detalhes bibliográficos
Main Authors: Vouillamoz, Jacques, Entenza, José M., Hohl, Peter, Moreillon, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525417/
https://ncbi.nlm.nih.gov/pubmed/15504859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4322-4327.2004
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