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DM-BLD: differential methylation detection using a hierarchical Bayesian model exploiting local dependency

MOTIVATION: The advent of high-throughput DNA methylation profiling techniques has enabled the possibility of accurate identification of differentially methylated genes for cancer research. The large number of measured loci facilitates whole genome methylation study, yet posing great challenges for...

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Библиографические подробности
Опубликовано в: :Bioinformatics
Главные авторы: Wang, Xiao, Gu, Jinghua, Hilakivi-Clarke, Leena, Clarke, Robert, Xuan, Jianhua
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5254079/
https://ncbi.nlm.nih.gov/pubmed/27616707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw596
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