ロード中...
Predictions of Ligand Selectivity from Absolute Binding Free Energy Calculations
[Image: see text] Binding selectivity is a requirement for the development of a safe drug, and it is a critical property for chemical probes used in preclinical target validation. Engineering selectivity adds considerable complexity to the rational design of new drugs, as it involves the optimizatio...
保存先:
| 出版年: | J Am Chem Soc |
|---|---|
| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2016
|
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5253712/ https://ncbi.nlm.nih.gov/pubmed/28009512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11467 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|