Gamma-irradiation produces active chlorine species (ACS) in physiological solutions: Secoisolariciresinol diglucoside (SDG) scavenges ACS - A novel mechanism of DNA radioprotection

BACKGROUND: Secoisolariciresinol diglucoside (SDG), the main lignan in whole grain flaxseed, is a potent antioxidant and free radical scavenger with known radioprotective properties. However, the exact mechanism of SDG radioprotection is not well understood. The current study identified a novel mech...

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Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Mishra, Om P., Popov, Anatoliy V., Pietrofesa, Ralph A., Christofidou-Solomidou, Melpo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253237/
https://ncbi.nlm.nih.gov/pubmed/27261092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.05.037
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