Adjusting Overall Survival Estimates after Treatment Switching: a Case Study in Metastatic Castration-Resistant Prostate Cancer

BACKGROUND: If patients in oncology trials receive subsequent therapy, standard intention-to-treat (ITT) analyses may inaccurately estimate the overall survival (OS) effect of the investigational product. In this context, a post-hoc analysis of the phase 3 PREVAIL study was performed with the aim to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Target Oncol
Prif Awduron: Skaltsa, Konstantina, Ivanescu, Cristina, Naidoo, Shevani, Phung, De, Holmstrom, Stefan, Latimer, Nicholas R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2016
Pynciau:
Original Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253154/
https://ncbi.nlm.nih.gov/pubmed/27981431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-016-0472-3
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