Immunization with Modified Vaccinia Virus Ankara-Based Recombinant Vaccine against Severe Acute Respiratory Syndrome Is Associated with Enhanced Hepatitis in Ferrets

Severe acute respiratory syndrome (SARS) caused by a newly identified coronavirus (SARS-CoV) is a serious emerging human infectious disease. In this report, we immunized ferrets (Mustela putorius furo) with recombinant modified vaccinia virus Ankara (rMVA) expressing the SARS-CoV spike (S) protein....

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Detalhes bibliográficos
Main Authors: Weingartl, Hana, Czub, Markus, Czub, Stefanie, Neufeld, James, Marszal, Peter, Gren, Jason, Smith, Greg, Jones, Shane, Proulx, Roxanne, Deschambault, Yvonne, Grudeski, Elsie, Andonov, Anton, He, Runtao, Li, Yan, Copps, John, Grolla, Allen, Dick, Daryl, Berry, Jody, Ganske, Shelley, Manning, Lisa, Cao, Jingxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525089/
https://ncbi.nlm.nih.gov/pubmed/15507655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.22.12672-12676.2004
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