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EBNA2 Is Required for Protection of Latently Epstein-Barr Virus-Infected B Cells against Specific Apoptotic Stimuli

In addition to functioning as a transcriptional transactivator, Epstein-Barr virus EBNA2 interacts with Nur77 to protect against Nur77-mediated apoptosis. Estrogen-regulated EBNA2 in EREB2-5 cells was replaced by either EBNA2 or EBNA2 with a deletion of conserved region 4 (EBNA2ΔCR4). Both EBNA2-con...

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Detalhes bibliográficos
Main Authors: Lee, Jae Myun, Lee, Kyoung-Ho, Farrell, Christopher J., Ling, Paul D., Kempkes, Bettina, Park, Jeon Han, Hayward, S. Diane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525073/
https://ncbi.nlm.nih.gov/pubmed/15507659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.22.12694-12697.2004
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