Construction of a Herpes Simplex Virus Type 1 Mutant with Only a Three-Nucleotide Change in the Branchpoint Region of the Latency-Associated Transcript (LAT) and the Stability of Its Two-Kilobase LAT Intron

Previous studies using a eukaryotic expression system indicated that the unusual stability of the latency-associated transcript (LAT) intron was due to its nonconsensus branchpoint sequence (T.-T Wu, Y.-H. Su, T. M. Block, and J. M. Taylor, Virology, 243:140-149, 1998). The present study investigate...

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Detalhes bibliográficos
Main Authors: Ng, Alan K., Block, Timothy M., Aiamkitsumrit, Benjamas, Wang, Mengjun, Clementi, Emily, Wu, Ting-Ting, Taylor, John M., Su, Ying-Hsiu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525071/
https://ncbi.nlm.nih.gov/pubmed/15507596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.22.12097-12106.2004
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