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Leptin influences estrogen metabolism and increases DNA adduct formation in breast cancer cells

OBJECTIVE: The elevated incidence of obesity has been paralleled with higher risks of breast cancer. High adiposity increases leptin secretion from adipose tissue, which in turn increases cancer cell proliferation. The interplay between leptin and estrogen is one of the mechanisms through which lept...

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Detalhes bibliográficos
Publicado no:Cancer Biol Med
Main Authors: Shouman, Samia, Wagih, Mohamed, Kamel, Marwa
Formato: Artigo
Idioma:Inglês
Publicado em: the Editorial Committee of Cancer Biology & Medicine 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250609/
https://ncbi.nlm.nih.gov/pubmed/28154783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2016.0079
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