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ER stress and impaired autophagy flux in neuronal degeneration and brain injury
Autophagy is a highly controlled lysosome-mediated function in eukaryotic cells to eliminate damaged or aged long-lived proteins and organelles. It is required for restoring cellular homeostasis in cell survival under multiple stresses. Autophagy is known to be a double-edged sword because too much...
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| Publicado no: | Ageing Res Rev |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5250579/ https://ncbi.nlm.nih.gov/pubmed/27594375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2016.08.008 |
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