JNK Regulates the Release of Proapoptotic Mitochondrial Factors in Reovirus-Infected Cells

Reovirus-induced apoptosis is associated with activation of the proapoptotic mitogen-activated protein kinase c-Jun N-terminal kinase (JNK) and the JNK-associated transcription factor c-Jun. Here we show that reovirus-induced apoptosis and activation of caspase 3 are inhibited in cells deficient in...

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Autors principals: Clarke, Penny, Meintzer, Suzanne M., Wang, Yibing, Moffitt, Lisa A., Richardson-Burns, Sarah M., Johnson, Gary L., Tyler, Kenneth L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC524973/
https://ncbi.nlm.nih.gov/pubmed/15542665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.13132-13138.2004
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