Resistance to Vesicular Stomatitis Virus Infection Requires a Functional Cross Talk between the Eukaryotic Translation Initiation Factor 2α Kinases PERK and PKR

Phosphorylation of the alpha (α) subunit of the eukaryotic translation initiation factor 2 (eIF2) leads to the inhibition of protein synthesis in response to diverse stress conditions, including viral infection. The eIF2α kinase PKR has been shown to play an essential role against vesicular stomatit...

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Autores principales: Baltzis, Dionissios, Qu, Li-Ke, Papadopoulou, Stavroula, Blais, Jaime D., Bell, John C., Sonenberg, Nahum, Koromilas, Antonis E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC524969/
https://ncbi.nlm.nih.gov/pubmed/15542627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.12747-12761.2004
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