Combination of Lipitor and Celebrex Inhibits Prostate Cancer VCaP Cells In Vitro and In Vivo

BACKGROUND/AIM: Lipitor is a cholesterol-lowering drug and Celebrex is a cyclooxygenase 2 inhibitor. We investigated the effects of Lipitor and Celebrex on human prostate cancer VCaP cells cultured in vitro and grown as orthotopic xenograft tumors in SCID mice. MATERIALS AND METHODS: Apoptosis was m...

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Detalhes bibliográficos
Publicado no:Anticancer Res
Main Authors: Huang, Huarong, Cui, Xiao-Xing, Chen, Shaohua, Goodin, Susan, Liu, Yue, He, Yan, Li, Dongli, Wang, Hong, Van Doren, Jeremiah, DiPaola, Robert S, Conney, Allan H., Zheng, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249253/
https://ncbi.nlm.nih.gov/pubmed/24982340
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