Weight Perturbation Alters Leptin Signal Transduction in a Region-Specific Manner throughout the Brain

Diet-induced obesity (DIO) resulting from consumption of a high fat diet (HFD) attenuates normal neuronal responses to leptin and may contribute to the metabolic defense of an acquired higher body weight in humans; the molecular bases for the persistence of this defense are unknown. We measured the...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Morabito, Michael V., Ravussin, Yann, Mueller, Bridget R., Skowronski, Alicja A., Watanabe, Kazuhisa, Foo, Kylie S., Lee, Samuel X., Lehmann, Anders, Hjorth, Stephan, Zeltser, Lori M., LeDuc, Charles A., Leibel, Rudolph L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249166/
https://ncbi.nlm.nih.gov/pubmed/28107353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168226
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