Systemic T Cells Immunosuppression of Glioma Stem Cell-Derived Exosomes Is Mediated by Monocytic Myeloid-Derived Suppressor Cells

A major contributing factor to glioma development and progression is its ability to evade the immune system. Nano-meter sized vesicles, exosomes, secreted by glioma-stem cells (GSC) can act as mediators of intercellular communication to promote tumor immune escape. Here, we investigated the immunomo...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Domenis, Rossana, Cesselli, Daniela, Toffoletto, Barbara, Bourkoula, Evgenia, Caponnetto, Federica, Manini, Ivana, Beltrami, Antonio Paolo, Ius, Tamara, Skrap, Miran, Di Loreto, Carla, Gri, Giorgia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249124/
https://ncbi.nlm.nih.gov/pubmed/28107450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169932
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