Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy.

To study the mechanisms that activate expression of the atrial natriuretic factor (ANF) gene during pressure-induced hypertrophy, we have developed and characterized an in vivo murine model of myocardial cell hypertrophy. We employed microsurgical techniques to produce a stable 35- to 45-mmHg pressu...

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Bibliographic Details
Main Authors: Rockman, H A, Ross, R S, Harris, A N, Knowlton, K U, Steinhelper, M E, Field, L J, Ross, J, Chien, K R
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC52490/
https://ncbi.nlm.nih.gov/pubmed/1832775
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