Induction of Pulmonary Granuloma Formation by Propionibacterium acnes Is Regulated by MyD88 and Nox2

Sarcoidosis is characterized by noncaseating granulomas with an unknown cause that present primarily in the lung. Propionibacterium acnes, an immunogenic commensal skin bacterium involved in acne vulgaris, has been implicated as a possible causative agent of sarcoidosis. Here, we demonstrate that a...

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Vydáno v:Am J Respir Cell Mol Biol
Hlavní autoři: Werner, Jessica L., Escolero, Sylvia G., Hewlett, Jeff T., Mak, Tim N., Williams, Brian P., Eishi, Yoshinobu, Núñez, Gabriel
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2017
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248957/
https://ncbi.nlm.nih.gov/pubmed/27607191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0035OC
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