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Generation of Compartmentalized Pressure by a Nuclear Piston Governs Cell Motility in 3D Matrix()

Cells use actomyosin contractility to move through three-dimensional (3D) extracellular matrix. Contractility affects the type of protrusions cells use to migrate in 3D, but the mechanisms are unclear. Here we found that contractility generated high-pressure lobopodial protrusions in cells migrating...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Petrie, Ryan J., Koo, Hyun, Yamada, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248932/
https://ncbi.nlm.nih.gov/pubmed/25170155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1256965
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