Emergency use of uridine triacetate for the prevention and treatment of life‐threatening 5‐fluorouracil and capecitabine toxicity

BACKGROUND: Increased susceptibility to 5‐fluorouracil (5‐FU)/capecitabine can lead to rapidly occurring toxicity caused by impaired clearance, dihydropyrimidine dehydrogenase deficiency, and other genetic variations in the enzymes that metabolize 5‐FU. Life‐threatening 5‐FU overdoses occur because...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer
Asıl Yazarlar: Ma, Wen Wee, Saif, Muhammad Wasif, El‐Rayes, Bassel F., Fakih, Marwan G., Cartwright, Thomas H., Posey, James A., King, Thomas R., von Borstel, Reid W., Bamat, Michael K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248610/
https://ncbi.nlm.nih.gov/pubmed/27622829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30321
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