Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure.

Virus-induced acquired immune suppression in mice infected with lymphocytic choriomeningitis virus is shown here to be caused by the CD8+-T-cell-dependent elimination of macrophages/antigen-presenting cells. Surprisingly, this is associated with severe destruction of the follicular organization of l...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Odermatt, B, Eppler, M, Leist, T P, Hengartner, H, Zinkernagel, R M
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1991
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1910175/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.18.8252
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