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Potential implication of the chemical properties and bioactivity of nitrone spin traps for therapeutics

Nitrone therapeutics has been employed in the treatment of oxidative stress-related diseases such as neurodegeneration, cardiovascular disease and cancer. The nitrone-based compound NXY-059, which is the first drug to reach clinical trials for the treatment of acute ischemic stroke, has provided pro...

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Détails bibliographiques
Publié dans:Future Med Chem
Auteurs principaux: Villamena, Frederick A, Das, Amlan, Nash, Kevin M
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248478/
https://ncbi.nlm.nih.gov/pubmed/22709256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.74
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