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Stepwise addition of genetic changes correlated with histological change from “well-differentiated” to “sarcomatoid” phenotypes: a case report

BACKGROUND: Sarcomatoid cancer is defined by the World Health Organization as a category of non-small cell lung cancers with sarcoma or sarcoma-like differentiation. They are characterized by poor prognosis and resistance to conventional chemotherapy. However, the mutational profile of sarcomatoid c...

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Библиографические подробности
Опубликовано в: :BMC Cancer
Главные авторы: Goto, Taichiro, Hirotsu, Yosuke, Mochizuki, Hitoshi, Nakagomi, Takahiro, Oyama, Toshio, Amemiya, Kenji, Omata, Masao
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248474/
https://ncbi.nlm.nih.gov/pubmed/28103823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3059-1
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