Combining biological networks to predict genetic interactions

Genetic interactions define overlapping functions and compensatory pathways. In particular, synthetic sick or lethal (SSL) genetic interactions are important for understanding how an organism tolerates random mutation, i.e., genetic robustness. Comprehensive identification of SSL relationships remai...

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Detalhes bibliográficos
Main Authors: Wong, Sharyl L., Zhang, Lan V., Tong, Amy H. Y., Li, Zhijian, Goldberg, Debra S., King, Oliver D., Lesage, Guillaume, Vidal, Marc, Andrews, Brenda, Bussey, Howard, Boone, Charles, Roth, Frederick P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524818/
https://ncbi.nlm.nih.gov/pubmed/15496468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406614101
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