Combining biological networks to predict genetic interactions

Genetic interactions define overlapping functions and compensatory pathways. In particular, synthetic sick or lethal (SSL) genetic interactions are important for understanding how an organism tolerates random mutation, i.e., genetic robustness. Comprehensive identification of SSL relationships remai...

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Détails bibliographiques
Auteurs principaux: Wong, Sharyl L., Zhang, Lan V., Tong, Amy H. Y., Li, Zhijian, Goldberg, Debra S., King, Oliver D., Lesage, Guillaume, Vidal, Marc, Andrews, Brenda, Bussey, Howard, Boone, Charles, Roth, Frederick P.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC524818/
https://ncbi.nlm.nih.gov/pubmed/15496468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406614101
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