Combining biological networks to predict genetic interactions

Genetic interactions define overlapping functions and compensatory pathways. In particular, synthetic sick or lethal (SSL) genetic interactions are important for understanding how an organism tolerates random mutation, i.e., genetic robustness. Comprehensive identification of SSL relationships remai...

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Bibliografiska uppgifter
Huvudupphovsmän: Wong, Sharyl L., Zhang, Lan V., Tong, Amy H. Y., Li, Zhijian, Goldberg, Debra S., King, Oliver D., Lesage, Guillaume, Vidal, Marc, Andrews, Brenda, Bussey, Howard, Boone, Charles, Roth, Frederick P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2004
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC524818/
https://ncbi.nlm.nih.gov/pubmed/15496468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406614101
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