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Secreted miR-27a Induced by Cyclic Stretch Modulates the Proliferation of Endothelial Cells in Hypertension via GRK6

Abnormal proliferation of endothelial cells (ECs) is important in vascular remodeling during hypertension, but the mechanisms are still unclear. In hypertensive rats caused by abdominal aortic coarctation, the expression of G-protein-coupled receptor kinase 6 (GRK6) in ECs at common carotid artery w...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Lu, Bao, Han, Wang, Kai-Xuan, Zhang, Ping, Yao, Qing-Ping, Chen, Xiao-Hu, Huang, Kai, Qi, Ying-Xin, Jiang, Zong-Lai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247685/
https://ncbi.nlm.nih.gov/pubmed/28106155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41058
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