Bikunin Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor Alpha Induction in Macrophages

Bikunin, a Kunitz-type protease inhibitor, exhibits anti-inflammatory activity in protection against cancer and inflammation. To investigate the molecular mechanism of this inhibition, we analyzed the effect of bikunin on tumor necrosis factor alpha (TNF-α) production in human peripheral mononuclear...

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Autors principals: Matsuzaki, Hidenori, Kobayashi, Hiroshi, Yagyu, Tatsuo, Wakahara, Kiyoshi, Kondo, Toshiharu, Kurita, Noriyuki, Sekino, Hideo, Inagaki, Kiyokazu, Suzuki, Mika, Kanayama, Naohiro, Terao, Toshihiko
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Microbial Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC524767/
https://ncbi.nlm.nih.gov/pubmed/15539519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.11.6.1140-1147.2004
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