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Structural Insights into Inhibition of Escherichia coli Penicillin-binding Protein 1B
In Escherichia coli, the peptidoglycan cell wall is synthesized by bifunctional penicillin-binding proteins such as PBP1b that have both transpeptidase and transglycosylase activities. The PBP1b transpeptidase domain is a major target of β-lactams, and therefore it is important to attain a detailed...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5247669/ https://ncbi.nlm.nih.gov/pubmed/27899450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.718403 |
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