A Venom Serpin Splicing Isoform of the Endoparasitoid Wasp Pteromalus puparum Suppresses Host Prophenoloxidase Cascade by Forming Complexes with Host Hemolymph Proteinases

To ensure successful parasitism, parasitoid wasps inject venom along with their eggs into their hosts. The venom serves to suppress host immune responses, including melanization. Venom from Pteromalus puparum, a pupal endoparasitoid, inhibits melanization of host hemolymph in vitro in a dose-depende...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Yan, Zhichao, Fang, Qi, Liu, Yang, Xiao, Shan, Yang, Lei, Wang, Fei, An, Chunju, Werren, John H., Ye, Gongyin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2017
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247638/
https://ncbi.nlm.nih.gov/pubmed/27913622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.739565
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