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GLP-1R Signaling Directly Activates Arcuate Nucleus Kisspeptin Action in Brain Slices but Does not Rescue Luteinizing Hormone Inhibition in Ovariectomized Mice During Negative Energy Balance

Kisspeptin (Kiss1) neurons in the hypothalamic arcuate nucleus (ARC) are key components of the hypothalamic-pituitary-gonadal axis, as they regulate the basal pulsatile release of gonadotropin releasing hormone (GnRH). ARC Kiss1 action is dependent on energy status, and unmasking metabolic factors r...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Heppner, Kristy M., Baquero, Arian F., Bennett, Camdin M., Lindsley, Sarah R., Kirigiti, Melissa A., Bennett, Baylin, Bosch, Martha A., Mercer, Aaron J., Rønnekleiv, Oline K., True, Cadence, Grove, Kevin L., Smith, M. Susan
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247618/
https://ncbi.nlm.nih.gov/pubmed/28144621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0198-16.2016
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