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Schizosaccharomyces pombe RanGAP Homolog, SpRna1, Is Required for Centromeric Silencing and Chromosome Segregation
We isolated 11 independent temperature-sensitive (ts) mutants of Schizosaccharomyces pombe RanGAP, SpRna1 that have several amino acid changes in the conserved domains of RanGAP. Resulting Sprna1(ts) showed a strong defect in mitotic chromosome segregation, but did not in nucleocytoplasmic transport...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Cell Biology
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524752/ https://ncbi.nlm.nih.gov/pubmed/15317843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-01-0067 |
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