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Schizosaccharomyces pombe RanGAP Homolog, SpRna1, Is Required for Centromeric Silencing and Chromosome Segregation

We isolated 11 independent temperature-sensitive (ts) mutants of Schizosaccharomyces pombe RanGAP, SpRna1 that have several amino acid changes in the conserved domains of RanGAP. Resulting Sprna1(ts) showed a strong defect in mitotic chromosome segregation, but did not in nucleocytoplasmic transport...

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Detalhes bibliográficos
Main Authors: Kusano, Ayumi, Yoshioka, Tomoko, Nishijima, Hitoshi, Nishitani, Hideo, Nishimoto, Takeharu
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524752/
https://ncbi.nlm.nih.gov/pubmed/15317843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-01-0067
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