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A first-order reaction controls the binding of antigenic peptides to major histocompatibility complex class II molecules.

Major histocompatibility complex class II molecules have been reported to bind antigenic peptides very slowly in vitro. To investigate the molecular events that govern the slow binding reaction, we have determined the dependence of complex formation and dissociation on peptide concentration. The com...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Witt, S N, McConnell, H M
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52467/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1654561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.18.8164
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