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Effect of the Protein Corona on Antibody–Antigen Binding in Nanoparticle Sandwich Immunoassays

We investigated the effect of the protein corona on the function of nanoparticle (NP) antibody (Ab) conjugates in dipstick sandwich immunoassays. Ab specific for Zika virus nonstructural protein 1 (NS1) were conjugated to gold NPs, and another anti-NS1 Ab was immobilized onto the nitrocellulose memb...

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Detalles Bibliográficos
Publicado en:Bioconjug Chem
Main Authors: de Puig, Helena, Bosch, Irene, Carré-Camps, Marc, Hamad-Schifferli, Kimberly
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245486/
https://ncbi.nlm.nih.gov/pubmed/28095684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00523
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