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On modeling locus heterogeneity using mixture distributions

BACKGROUND: Locus heterogeneity poses a major difficulty in mapping genes that influence complex genetic traits. A widely used approach to deal with this problem involves modeling linkage data in terms of finite mixture distributions. In its simplest setup, also known as the admixture approach, a si...

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Detalhes bibliográficos
Main Authors: Lin, Shili, Biswas, Swati
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524512/
https://ncbi.nlm.nih.gov/pubmed/15458576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-5-29
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