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Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin‐binding protein PonA1 reveal potential mechanisms of antibiotic resistance

Mycobacterium tuberculosis is a human respiratory pathogen that causes the deadly disease tuberculosis. The rapid global spread of antibiotic‐resistant M. tuberculosis makes tuberculosis infections difficult to treat. To overcome this problem new effective antimicrobial strategies are urgently neede...

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Bibliografski detalji
Izdano u:FEBS J
Glavni autori: Filippova, Ekaterina V., Kieser, Karen J., Luan, Chi‐Hao, Wawrzak, Zdzislaw, Kiryukhina, Olga, Rubin, Eric J., Anderson, Wayne F.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245116/
https://ncbi.nlm.nih.gov/pubmed/27101811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13738
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