Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin‐binding protein PonA1 reveal potential mechanisms of antibiotic resistance

Mycobacterium tuberculosis is a human respiratory pathogen that causes the deadly disease tuberculosis. The rapid global spread of antibiotic‐resistant M. tuberculosis makes tuberculosis infections difficult to treat. To overcome this problem new effective antimicrobial strategies are urgently neede...

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Vydáno v:FEBS J
Hlavní autoři: Filippova, Ekaterina V., Kieser, Karen J., Luan, Chi‐Hao, Wawrzak, Zdzislaw, Kiryukhina, Olga, Rubin, Eric J., Anderson, Wayne F.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245116/
https://ncbi.nlm.nih.gov/pubmed/27101811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13738
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