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Anti-tumor and anti-invasion effects of a combination of 4-methylumbelliferone and ionizing radiation in human fibrosarcoma cells

Hyaluronan (HA) is a major component of the extracellular matrix that is synthesized in excess in cancer tissues. 4-methylumbelliferone (MU) inhibits the synthesis of HA and is closely related to the invasion and metastasis of cancer. However, the effects of MU in conjunction with cancer radiotherap...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Saga, Ryo, Monzen, Satoru, Chiba, Mitsuru, Yoshino, Hironori, Nakamura, Toshiya, Hosokawa, Yoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245070/
https://ncbi.nlm.nih.gov/pubmed/28123575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5385
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