Safety and efficacy of fruquintinib in patients with previously treated metastatic colorectal cancer: a phase Ib study and a randomized double-blind phase II study

BACKGROUND: To assess the efficacy and safety of fruquintinib, a vascular endothelial growth factor receptor (VEGFR) inhibitor, in metastatic colorectal cancer (mCRC) patients. METHODS: A phase Ib open-label study and phase II randomized, placebo-controlled trial compared the efficacy of fruquintini...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Xu, Rui-Hua, Li, Jin, Bai, Yuxian, Xu, Jianming, Liu, Tianshu, Shen, Lin, Wang, Liwei, Pan, Hongming, Cao, Junning, Zhang, Dongsheng, Fan, Songhua, Hua, Ye, Su, Weiguo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244709/
https://ncbi.nlm.nih.gov/pubmed/28103904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0384-9
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