Label‐free live cell imaging by Confocal Raman Microscopy identifies CHO host and producer cell lines

As a possible viable and non‐invasive method to identify high producing cells, Confocal Raman Microscopy was shown to be able to differentiate CHO host cell lines and derivative production clones. Cluster analysis of spectra and their derivatives was able to differentiate between different producer...

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Bibliographische Detailangaben
Veröffentlicht in:Biotechnol J
Hauptverfasser: Prats Mateu, Batirtze, Harreither, Eva, Schosserer, Markus, Puxbaum, Verena, Gludovacz, Elisabeth, Borth, Nicole, Gierlinger, Notburga, Grillari, Johannes
Format: Artigo
Sprache:Inglês
Veröffentlicht: WILEY‐VCH Verlag 2016
Schlagworte:
Biotech Methods
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244663/
https://ncbi.nlm.nih.gov/pubmed/27440252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201600037
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