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Genomic rearrangement screening of the BRCA1 from seventy Iranian high-risk breast cancer families

BACKGROUND: The second leading cause of cancer deaths in women is breast cancer. Germline mutations in susceptibility breast cancer gene BRCA1 increase the lifetime risk of breast cancer. Eighty-one large genomic rearrangements (LGRs) have been reported up to date in BRCA1 gene, and evaluation of th...

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Detalhes bibliográficos
Publicado no:J Res Med Sci
Main Authors: Sedghi, Maryam, Esfandiari, Elham, Fazel-Najafabadi, Esmat, Salehi, Mansoor, Salavaty, Abbas, Fattahpour, Shirin, Dehghani, Leila, Nouri, Nayerossadat, Mokarian, Fariborz
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244654/
https://ncbi.nlm.nih.gov/pubmed/28163741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-1995.193167
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