RNA interference mediated knockdown of Brugia malayi UDP-Galactopyranose mutase severely affects parasite viability, embryogenesis and in vivo development of infective larvae

BACKGROUND: Galactofuranose is an essential cell surface component present in bacteria, fungi and several nematodes such as Caenorhabditis spp., Brugia spp., Onchocerca spp. and Strongyloides spp. This sugar maintains the integrity of parasite surface and is essential for virulence. UDP-Galactopyran...

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Publicado en:Parasit Vectors
Autores principales: Misra, Sweta, Gupta, Jyoti, Misra-Bhattacharya, Shailja
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244609/
https://ncbi.nlm.nih.gov/pubmed/28103957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-017-1967-1
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