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Production of 2-Hydroxyisobutyric Acid from Methanol by Methylobacterium extorquens AM1 Expressing (R)-3-Hydroxybutyryl Coenzyme A-Isomerizing Enzymes

The biotechnological production of the methyl methacrylate precursor 2-hydroxyisobutyric acid (2-HIBA) via bacterial poly-3-hydroxybutyrate (PHB) overflow metabolism requires suitable (R)-3-hydroxybutyryl coenzyme A (CoA)-specific coenzyme B(12)-dependent mutases (RCM). Here, we characterized a pred...

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書目詳細資料
發表在:Appl Environ Microbiol
Main Authors: Rohde, Maria-Teresa, Tischer, Sylvi, Harms, Hauke, Rohwerder, Thore
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244315/
https://ncbi.nlm.nih.gov/pubmed/27836853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02622-16
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