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Gene targeting in yeast is initiated by two independent strand invasions
To study the mechanism of gene targeting, we examined heteroduplex DNA (hDNA) formation during targeting of two separate chromosomal locations in Saccharomyces cerevisiae. We examined both replacement of the entire gene with a heterologous selectable marker and correction of a single base pair inser...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524428/ https://ncbi.nlm.nih.gov/pubmed/15489271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403748101 |
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