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High-Content Screening Microscopy Identifies Novel Proteins With a Putative Role in Secretory Membrane Traffic

Here we describe the establishment of microscope-based functional screening assays in intact cells that allow us to systematically identify new proteins involved in secretory membrane traffic, and proteins that can influence the integrity of the Golgi complex. We were able to identify 20 new protein...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Starkuviene, Vytaute, Liebel, Urban, Simpson, Jeremy C., Erfle, Holger, Poustka, Annemarie, Wiemann, Stefan, Pepperkok, Rainer
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC524419/
https://ncbi.nlm.nih.gov/pubmed/15466293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2658304
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