Calculating the optimal surveillance for head and neck paraganglioma in SDHB-mutation carriers

Germline mutations of the gene encoding succinate dehydrogenase subunit B (SDHB) predispose to head-and-neck-paraganglioma (HNPGL), sympathetic PGL, pheochromocytoma and renal cell carcinoma for which regular surveillance is required. SDHB-associated tumors harbor germline and somatic mutations, con...

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Publicado en:Fam Cancer
Autores principales: Eijkelenkamp, Karin, Osinga, Thamara E., de Jong, Mirjam M., Sluiter, Wim J., Dullaart, Robin P. F., Links, Thera P., Kerstens, Michiel N., van der Horst-Schrivers, Anouk N. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243881/
https://ncbi.nlm.nih.gov/pubmed/27573198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-016-9923-3
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