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Enzymatic Incorporation and Utilization of an Emissive 6-Aza Uridine

To display favorable fluorescent properties, the non-emissive native nucleosides need to be modified. Here we present a motif that relies on conjugating 5-membered aromatic heterocycles (e.g., thiophene) to a 6-azapyrimidine (1,2,4-triazine) core. Synthetic accessibility and desirable photophysical...

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Bibliografske podrobnosti
izdano v:Org Biomol Chem
Main Authors: Hopkins, Patrycja A., McCoy, Lisa S., Tor, Yitzhak
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243813/
https://ncbi.nlm.nih.gov/pubmed/27981333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob02080a
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