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The fallacy of enrolling only high-risk subjects in cancer prevention trials: Is there a "free lunch"?

BACKGROUND: There is a common belief that most cancer prevention trials should be restricted to high-risk subjects in order to increase statistical power. This strategy is appropriate if the ultimate target population is subjects at the same high-risk. However if the target population is the general...

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Bibliografiska uppgifter
Huvudupphovsmän: Baker, Stuart G, Kramer, Barnett S, Corle, Donald
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2004
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC524373/
https://ncbi.nlm.nih.gov/pubmed/15461821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-4-24
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